About 13 results found for searched term "OM99-2" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M52422 | OM99-2 | Gamma-secretase/Beta-secretase |
| OM99-2, an eight residue peptidomimetic, tight-binding inhibitor of human brain memapsin 2 with a Ki value of 9.58 nM. | ||
| M52424 | OM99-2 TFA | Gamma-secretase/Beta-secretase |
| OM99-2 TFA, an eight residue peptidomimetic, tight-binding inhibitor of human brain memapsin 2 with a Ki value of 9.58 nM. | ||
| M1869 | Dacomitinib | EGFR/HER2 |
| PF-00299804 | ||
| Dacomitinib (PF-00299804) is an oral, irreversible, small molecule inhibitor of human epidermal growth factor receptor-1, -2, and -4 tyrosine kinases. | ||
| M5827 | Oclacitinib maleate | JAK |
| PF-03394197 | ||
| Oclacitinib is a novel inhibitor of JAK family members with IC50 ranging from 10 to 99 nM and JAK1-dependent cytokines with IC50 ranging from 36 to 249 nM, which did not inhibit a panel of 38 non-JAK kinases. | ||
| M14633 | Isocurcumenol | Estrogen Receptor |
| Isocurcumenol, an estrogen receptor alpha (ERα) inhibitor isolated from Curcuma zedoaria Rhizomes, possesses anti-tumor acticity, with IC50 values of 99.1µg/mL and 178.2 µg/mL in DLA and KB cells, respectively. | ||
| M19979 | MitoTracker Red CMXRos | Fluorescent Dye |
| Chloromethyl-X-rosamine | ||
| Mitotracker red cmxros is a red fluorescent dye used for staining mitochondria of living cells. Mitotracker red cmxros is a cell permeable x-rosamine derivative containing a weakly thiol reactive chloromethyl functional group that marks mitochondria. The maximum excitation / emission wavelength is 579 / 599nm- At 20 ℃, it shall be sealed and dried in a dark and moisture-proof manner. | ||
| M20630 | ex229 (compound 991) | AMPK |
| EX229 (compound 991) is a potent AMPK activator that is 5-10-fold more potent than A769662 in activating AMPK. | ||
| M21353 | Golcadomide | Ligand for E3 Ligase |
| CC-99282 | ||
| Golcadomide (CC-99282) is a potent and orally active CRBN E3 ligase modulator (CELMoD).CC-99282 co-induces effective and targeted degradation of Ikaros and Aiolos with CRBN.CC-99282 can be used in studies of non-Hodgkin's lymphoma. | ||
| M24722 | Bectumomab | Others |
| IMMU-LL 2 | ||
| Bectumomab (IMMU-LL 2) is an humanized IgG2a mAb against human CD22 (antigen). Bectumomab is also an anti-lymphoma antibody fragment. Bectumomab can be used for imaging in combination with technetium 99 (Tc99m LL2 Fab). Moreover, Bectumomab examines in the staging of recurrent or newly diagnosed non-Hodgkin's lymphoma (NHL) and to assess targeting before radioimmunotherapy (RIT). | ||
| M28491 | MRT199665 | Salt-inducible Kinase |
| MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370. | ||
| M29458 | SJFα | PROTAC |
| SJFα is a 13-atom linker PROTAC based on von Hippel-Lindau ligand. SJFα degrades p38α with a DC50 of 7.16 nM, but is far less effective at degrading p38δ (DC50=299 nM) and does not degrade the other p38 isoforms (β and γ) at concentrations up to 2.5 µM. | ||
| M51711 | J5 peptide | Others |
| J5 peptide is an MBP inhibitor that competitively inhibits the binding of MBP85-99 to HLA-DR2. | ||
| M52555 | [pTyr5] EGFR (988-993) | Phosphatase |
| [pTyr5] EGFR (988-993) is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). | ||
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