About 1 result found for searched term "Naldemedine tosylate" (0.132 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28208 | Naldemedine tosylate | Opioid Receptor |
| S-297995 tosylate | ||
| Naldemedine (S-297995) tosylate is an orally active μ-opioid receptor antagonist (PAMORA). Naldemedine tosylate shows potent binding affinities (Ki=0.34, 0.43, 0.94 nM, respectively) and antagonist activities (IC50=25.57, 7.09, 16.1 nM, respectively) for recombinant human μ-, δ-, and κ- opioid receptors. Naldemedine can be used in opioid-induced constipation (OIC) research. | ||
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