About 1 result found for searched term "NVS-SM2 " (0.174 seconds)
Cat.No. | Name | Target |
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M28601 | NVS-SM2 | DNA/RNA Synthesis |
NVS-SM2 is a potent, orally active and brain-penetrant SMN2 splicing enhancer with an EC50 of 2 nM for SMN. NVS-SM2 enhances U1-pre-mRNA association. NVS-SM2 promotes exon 7 inclusion and restores normal survival motor neuron (SMN) protein expression. NVS-SM2 can be used for spinal muscular atrophy (SMA) research. |
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