About 8 results found for searched term "NSD-IN-2" (0.128 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M41698 | NSD-IN-2 | Histone Methyltransferase |
| NSD-IN-2 is a potent and irreversible NSD1 inhibitor. | ||
| M10796 | BI-9321 | Histone Methyltransferase |
| BI-9321 is a potent, selective, cell-active NSD3-PWWP1 antagonist,Kd The value is 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 specifically disrupts NSD3-PWWP1 interaction with histones in U2OS cells,IC50 1.2 μM. | ||
| M10797 | BI-9321 trihydrochloride | Others |
| BI-9321 trihydrochloride is a potent, selective, cell-active NSD3-PWWP1 antagonist,Kd The value is 166 nM. BI-9321 is not valid for NSD2-PWWP1 and NSD3-PWWP2. BI-9321 trihydrochloride specifically disrupts NSD3-PWWP1 interaction with histones in U2OS cells,IC50 1.2 μM. | ||
| M21589 | OM-153 | PARP |
| OM-153 is a potent, orally active tankyrase inhibitor with IC50 of 13 nM for tankyrase 1 and 2 nM for tankyrase 2 (TNKS1/2). OM-153 inhibited luciferase based Wnt/β-catenin signal transduction reporter activity with IC50 of 0.63 nM. OM-153 inhibits Wnt/β-catenin signal transduction and proliferation in COLO 320DM. | ||
| M25458 | UNC8153 | Others |
| UNC-8153 | ||
| UNC8153 is a novel NSD2-targeted degrader that potently and selectively reduces the cellular levels of both NSD2 protein and the H3K36me2 chromatin mark. | ||
| M27953 | MR837 | Histone Methyltransferase |
| MR837 is an inhibitor of NSD2-PWWP1. MR837 can bind with human nuclear receptor binding SET domain protein 2 (PWWP domain). | ||
| M29829 | NSD2-IN-1 | Apoptosis |
| NSD2-IN-1 (compound 38) is a potent and high selective NSD2-PWWP1 (nuclear receptor-binding SET domain 2-PWWP1) inhibitor, with an IC50 of 0.11 μM. NSD2-IN-1 can bind to NSD2-PWWP1 and then affect the expression of genes regulated by NSD2. NSD2-IN-1 induces apoptosis and cell cycle arrest. | ||
| M41696 | NSD2-IN-4 | Histone Methyltransferase |
| NSD2-IN-4 is a potent and selective NSD2-SET inhibitor. | ||
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