About 1 result found for searched term "NSC-658497 " (0.181 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30865 | NSC-658497 | Ras |
| NSC-658497 is an effective inhibitor of Ras-GEF, SOS1. NSC-658497 binds to SOS1, competitively suppresses SOS1-Ras interaction, and dose-dependently inhibits SOS1 GEF activity. NSC-658497 showed dose-dependent efficacy in inhibiting Ras, downstream signaling activities, and associated cell proliferation. | ||
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