About 4 results found for searched term "NLRP3-IN-10" (0.152 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M54571 | NLRP3-IN-10 | NLR |
| NLRP3-IN-10 is a potent NLRP3 inhibitor with an IC50 of 251.1 nM for inhibition of IL-1β. NLRP3-IN-10 attenuates the formation of ASC speckles and inhibits the activation of NLRP3 inflammatory vesicles. | ||
| M54574 | Emlenoflast | NLR |
| MCC7840 | ||
| Emlenoflast is a sulfonylurea compound that is also a potent and selective inhibitor of NLRP3 inflammatory vesicles with an IC50 value of less than 100 nM.Emlenoflast can be used in studies related to inflammatory diseases. | ||
| M54575 | Emlenoflast sodium | NLR |
| MCC7840 sodium | ||
| Emlenoflast sodium is a sulfonylurea and a potent and selective inhibitor of NLRP3 inflammatory vesicles with an IC50 value of less than 100 nM.Emlenoflast sodium can be used in the study of inflammatory diseases. | ||
| M54581 | NIC-0102 | Proteasome |
| NIC-0102 is an orally potent proteasome inhibitor (pIC50=7.55) that specifically inhibits NLRP3 inflammasome activation.NIC-0102 showed potent anti-inflammatory effects in vivo in a DSS-induced ulcerative colitis model. In addition, NIC-0102 inhibited the production of pro-IL-1β. | ||
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