About 9 results found for searched term "NI 42" (0.053 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1661 | AZD6244 | MEK |
| Selumetinib, ARRY-142886 | ||
| AZD6244 (ARRY-142886, Selumetinib) is a potent MEK 1/2 inhibitor with GI50 values ranging from 14 to 50 nM. | ||
| M1981 | Torkinib (PP242) | mTOR |
| Torkinib | ||
| Torkinib (PP242) is a selective, ATP-competitive mTORC1/mTORC2 inhibitor with IC50 of 8 nM. | ||
| M2053 | Wortmannin (KY 12420) | PI3K |
| SL-2052; KY-12420 | ||
| Wortmannin (KY 12420) is a specific, covalent inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) with IC50 of 3 nM. | ||
| M2468 | Brimonidine Tartrate | Adrenergic Receptor |
| Brimonidine tartrate; AGN190342 tartrate; UK14304 tartrate | ||
| Brimonidine Tartrate is a highly selective α-adrenergic receptor antagonist with an EC50 of 0.45 nM for α2A adrenoreceptor, and has been used to study open-angle glaucoma or ocular hypertension. | ||
| M3030 | S-Ruxolitinib | JAK |
| S-Ruxolitinib; INCB18424 | ||
| S-Ruxolitinib is the chirality of INCB018424, which is the first potent, selective, JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM, >130-fold selectivity for JAK1/2 versus JAK3. | ||
| M3491 | OSI-420 | EGFR/HER2 |
| Desmethyl Erlotinib; CP-473420 | ||
| OSI-420 is the active metabolite of Erlotinib (EGFR inhibitor with IC50 of 2 nM). | ||
| M7027 | NI 42 | Others |
| NI 42 is a high affinity BRPF inhibitor. | ||
| M10377 | Golidocitinib (AZD4205) | JAK |
| AZD-4205; Golidocitinib | ||
| Golidocitinib (AZD4205) is a novel potent and selective janus kinase 1 (JAK1) inhibitor, with IC50 value of 73 nM. | ||
| M51646 | Phosphorylase Kinase β-Subunit Fragment (420-436) | Others |
| Phosphorylase Kinase β-Subunit Fragment (420-436) is the β-Subunit fragment (peptide 430-436) of phosphorylase kinase. | ||
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