About 6 results found for searched term "NAV 26" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7018 | NAV 26 | Others |
| NAV 26 is a selective Na v1.7 channel blocker. | ||
| M1657 | Atazanavir Sulfate | HIV Protease |
| BMS-232632, Reyataz, CGP-73547 | ||
| Atazanavir sulfate (BMS-232632, Reyataz) is an azapeptide inhibitor of HIV-1 protease. Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. | ||
| M5427 | Atazanavir | HIV Protease |
| BMS-232632; Latazanavir; Zrivada; Reyataz | ||
| Atazanavir (BMS-232632) is an azapeptide and HIV-protease inhibitor. Atazanavir (BMS-232632) is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp). Atazanavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. | ||
| M8428 | PF-04856264 | Sodium Channel |
| PF04856264 | ||
| PF-04856264 is a potent and selective Nav1.7 inhibitor, with IC50s of 28, 131, 19, and 42 nM for human, mouse, cynomolgus monkey and dog Nav1.7, respectively. PF-04856264 has low potency against the rat Nav1.7 channel. | ||
| M10458 | Huwentoxin IV TFA | Sodium Channel |
| Huwentoxin-IV | ||
| Huwentoxin IV TFA is a selective NaV1.7 channel blocker, which preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM). | ||
| M52722 | Huwentoxin-IV | Sodium Channel |
| Huwentoxin-IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively. | ||
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