About 1 result found for searched term "N-Desmethyltamoxifen " (0.063 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29903 | N-Desmethyltamoxifen | PKC |
| N-Desmethyltamoxifen is the major metabolite of tamoxifen in humans. N-Desmethyltamoxifen, a poor antiestrogen, is a ten-fold more potent protein kinase C (PKC) inhibitor than Tamoxifen. N-Desmethyltamoxifen is also a potent regulator of ceramide metabolism in human AML cells, limiting ceramide glycosylation, hydrolysis, and sphingosine phosphorylation. | ||
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