About 3 results found for searched term "Mertansine" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M5222 | Mertansine | Microtubule |
| DM1, Maytansinoid | ||
| Mertansine is a tubulin inhibitor，inhibits the assembly of microtubules by binding to tubulin, with a linker structure can create an antibody-drug conjugate (ADC). *The compound is unstable in solutions, freshly prepared is recommended | ||
| M25224 | Cantuzumab mertansine | Drug-Linker Conjugates for ADC |
| SB-408075; huC242-DM1 | ||
| Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC, is an immunoconjugate of the potent maytansine derivative and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts. | ||
| M25214 | Lorvotuzumab | Others |
| Anti-NCAM1/CD56 Reference Antibody | ||
| Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds CD56 (NCAM1). Lorvotuzumab can be used to synthesize an ADC compound, Lorvotuzumab mertansine. | ||
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