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 About 4 results found for searched term "Melatonin-d4" (0.149 seconds)

Cat.No.  Name Target
M55436 Melatonin-d4 Melatonin Receptor
Melatonin-d4
M2230 Agomelatine Melatonin Receptor
Valdoxan; Melitor; S-20098
Agomelatine is a metabolically stable analog of melatonin that displays agonist activity for MT1 and MT2 binding with nanomolar affinity. Agomelatine is also a selective 5-HT2C receptor antagonist with pKis of 6.4 and 6.2 at native (porcine) and cloned, human 5-HT2C receptors, respectively.
M5919 Ramelteon (TAK-375) Melatonin Receptor
TAK-375
Ramelteon (TAK-375) is a novel melatonin receptor agonist for human MT1 and MT2 receptors and chick forebrain melatonin receptors with Ki of 14 pM, 112 pM and 23.1 pM, respectively.
M8769 Tasimelteon Melatonin Receptor
BMS-214778; VEC-162
Tasimelteon (BMS-214778) is a Dual Melatonin Receptor Agonist (DMRA) recently approved (Hetlioz) for the treatment of Non-24-hour sleep–wake disorder, a disorder primarily found in the totally blind, where a lack of normal synchronization between the 24-hour light–dark cycle and the endogenous circadian rhythm causes it to drift out of alignment with conventional sleep–wake schedules.



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