About 2 results found for searched term "Macitentan" (0.186 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2205 | Macitentan | Endothelin Receptor |
| ACT-064992 | ||
| Macitentan is an orally-active, tissue-targeting dual ET receptor antagonist. | ||
| M13956 | Aprocitentan | Endothelin Receptor |
| ACT-132577 | ||
| Aprocitentan (ACT-132577) is the major and pharmacologically active metabolite of Macitentan. Aprocitentan is dual ETA/ETB antagonist with IC50s of 3.4 nM and 987 nM, and pA2 valus of 6.7 and 5.5, respectively. | ||
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