About 2 results found for searched term "MSC2504877" (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28495 | MSC2504877 | PARP |
| M2912 | ||
| MSC2504877 (M2912) is a potent and orally active tankyrase inhibitor with IC50s of 0.0007, 0.0008, 0.54 µM for TNKS, TNKS2, PARP1, respectively. MSC2504877 increases the expression of AXIN2 and TNKS protein levels and decreases β-catenin levels. MSC2504877 shows anti-tumor activity. | ||
| M41571 | Tankyrase-IN-5 | PARP |
| Tankyrase-IN-5, an analogue of MSC2504877, is a tankyrase TNKS1 and TNKS2 inhibitor with IC50s of 2.3 nM and 7.9 nM, respectively. | ||
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