About 2 results found for searched term "MS4322" (0.124 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29725 | MS4322 (isomer) | PROTAC |
| YS43-22 (isomer) | ||
| MS4322 (YS43-22) isomer is an isomer of MS4322. MS4322 is a potent and selective PRMT5 (protein arginine methyltransferase 5) degrader, and inhibits growth of multiple cancer cell lines. | ||
| M58581 | MS4322 | PROTAC |
| YS43-22 | ||
| MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 μM in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. | ||
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