About 1 result found for searched term "MS31 trihydrochloride " (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M31013 | MS31 trihydrochloride | Epigenetic Reader Domain |
| MS31 trihydrochloride is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor. MS31 trihydrochloride potently inhibits the interactions between SPIN1 and H3K4me3 (IC50=77 nM, AlphaLISA; 243 nM, FP). MS31 trihydrochloride selectively binds Tudor domain II of SPIN1 (Kd=91 nM). MS31 trihydrochloride potently inhibits binding of trimethyllysine-containing peptides to SPIN1, and is not toxic to nontumorigenic cells. | ||
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