About 2 results found for searched term "MS21 " (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29560 | MS21 | PROTAC |
| MS21, a novel degrader of AKT, selectively inhibits the growth of PI3K/PTEN pathway-mutant cancers with wild-type KRAS and BRAF. | ||
| M30828 | BMS-688521 | Integrin |
| BMS-688521 is a highly potent, orally active inhibitor of the LFA-1/ICAM interaction, with an IC50 of 2.5 nM in the adhesion assay and an IC50 of 60 nM in the MLR assay. BMS-688521 is efficacious in a mouse allergic eosinophilic lung inflammation model. | ||
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