About 4 results found for searched term "MRT-10" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M8241 | MRT-10 | Others |
| MRT-10 is a novel, high-affinity antagonist of smoothened (Smo). | ||
| M10953 | MRTX-1719 | PRMTs |
| MRTX-1719 is a potent, first-of-its-kind, selective PRMT5/MTA complex inhibitor against PRMT5/MTA MTAPDEL SDMA CELL LINES IC50 The value is <10 nM. | ||
| M14052 | CCG-100602 | Ras |
| CCG-100602 is a specific inhibitor of myocardin-related transcription factor A/serum response factor (MRTF-A/SRF) signaling. CCG-100602 specifically block MRTF-A nuclear localization and thus inhibit the fibrogenic transcription factor SRF. | ||
| M28491 | MRT199665 | Salt-inducible Kinase |
| MRT199665 is a potent and ATP-competitive, selective MARK/SIK/AMPK inhibitor with IC50s of 2/2/3/2 nM, 10/10 nM, and 110/12/43 nM for MARK1/MARK2/MARK3/MARK14, AMPKα1/AMPKα2, and SIK1/SIK2/SIK3, respectively. MRT199665 causes apoptosis in MEF2C-activated human acute myeloid leukemias (AML) cells. MRT199665 inhibits the phosphorylation of SIK substrate CRTC3 at S370. | ||
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