About 5 results found for searched term "MN 64" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6986 | MN 64 | Others |
| MN 64 is a potent and selective tankyrase inhibitor. | ||
| M11537 | Nusinersen | DNA/RNA Synthesis |
| ASO-10-27 ; Ionis-SMNrx ; ISIS 396443 ; ISIS-SMNRx ; ISIS396443 | ||
| Nusinersen is an antisense oligonucleotide compound that modifies pre-messenger RNA splicing of the SMN2 gene, thereby promoting full-length SMN protein production. | ||
| M18925 | Dactylorhin A | Others |
| Dactylorhin A is a succinate derivative ester isolated from rhizomes of Gymnadenia conopsea. Dactylorhin A exhibits moderate inhibitory effects on NO production effects in RAW 264.7 macrophage cells. | ||
| M20687 | ETC-206 (AUM 001) | MNK |
| ETC-1907206 | ||
| ETC-206 is an orally available highly selective small-molecule MNK 1/2 inhibitor with IC50s of 64 nM and 86 nM, respectively. | ||
| M28295 | Ribocil | Antibiotic |
| Ribocil is a highly selective chemical modulator of bacterial riboflavin riboswitches. Ribocil strongly inhibits GFP expression, achieving a 50% effective concentration (EC50) of 0.3 μM. Target: in vitro: Ribocil is a highly specific bioactive synthetic mimic of FMN, which competes with the natural ligand to inhibit FMN riboswitch-mediated expression of ribB and inhibits bacterial growth. Ribocil-B demonstrates superior microbiological activity as compared to Ribocil-A (minimum inhibitory concentration (MIC) = 1 μg/ml versus MIC ≥ 64 μg/ml), inhibition of riboflavin synthesis (IC50 = 0.13 μM versus IC50 > 26 μM), and binding affinity to the E. coli FMN aptamer (Kd = 6.6 nM versus Kd ≥ 10,000 nM).[1] | ||
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