MLi-2 - Search Results | AbMole BioScience

About 5 results found for searched term "MLi-2" (0.124 seconds)

Cat.No.	Name	Target
M10595	MLi-2	LRRK2
	MLi2
	MLi-2 is a highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 (IC50 = 1.4 nM), and a radioligand competition binding assay (IC50 = 3.4 nM).
M21378	Sutimlimab	Complement System
	Sutimlimab is the first inhibitor of complement protein component 1,s subcomponent (C1s) for the study of cold agglutinin syndrome, a serine protease that cleaves C4 and C2 to form C3 convertase.
M25141	Iparomlimab	PD-1/PD-L1
	Iparomlimab is an anti-human PD-1/CD279/PDCD1 IgG4κ antibody. Iparomlimab also targets to human monoclonal PSB103 γ4-chain, disulfided with human monoclonal PSB103 κ-chain to form a dimer. Iparomlimab can be used for Oncology research.
M25420	Camlipixant	P2 Receptor
	BLU-5937
	Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric.
M28986	NI-57	Epigenetic Reader Domain
	NI-57 is an inhibitor of bromodomain and plant homeodomain finger-containing (BRPF) famlily of proteins, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.