About 5 results found for searched term "MLi-2" (0.126 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10595 | MLi-2 | LRRK2 |
| MLi2 | ||
| MLi-2 is a highly potent, and selective LRRK2 kinase inhibitor with central nervous system activity. MLi-2 exhibits exceptional potency in a purified LRRK2 kinase assay in vitro (IC50 = 0.76 nM), a cellular assay monitoring dephosphorylation of LRRK2 pSer935 LRRK2 (IC50 = 1.4 nM), and a radioligand competition binding assay (IC50 = 3.4 nM). | ||
| M21378 | Sutimlimab | Complement System |
| Sutimlimab is the first inhibitor of complement protein component 1,s subcomponent (C1s) for the study of cold agglutinin syndrome, a serine protease that cleaves C4 and C2 to form C3 convertase. | ||
| M25141 | Iparomlimab | PD-1/PD-L1 |
| Iparomlimab is an anti-human PD-1/CD279/PDCD1 IgG4κ antibody. Iparomlimab also targets to human monoclonal PSB103 γ4-chain, disulfided with human monoclonal PSB103 κ-chain to form a dimer. Iparomlimab can be used for Oncology research. | ||
| M25420 | Camlipixant | P2 Receptor |
| BLU-5937 | ||
| Camlipixant (BLU-5937) a potent, selective, non-competitive and orally active P2X3 homotrimeric receptor antagonist with an IC50 of 25 nM against hP2X3 homotrimeric. | ||
| M28986 | NI-57 | Epigenetic Reader Domain |
| NI-57 is an inhibitor of bromodomain and plant homeodomain finger-containing (BRPF) famlily of proteins, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively. | ||
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