About 1 result found for searched term "ML372 " (0.12 seconds)
Cat.No. | Name | Target |
---|---|---|
M28181 | ML372 | DNA/RNA Synthesis |
ML372 inhibits survival motor neuron (SMN) protein ubiquitination, increases SMN protein stability without affecting mRNA expression. ML372 improves spinal muscular atrophy (SMA) in mice. ML372 is brain penetrant and has a reasonable exposure and half-life in vivo. |
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