About 3 results found for searched term "ML351" (0.165 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M1828 | Tandutinib | FLT3 |
| MLN518, CT53518 | ||
| Tandutinib (MLN518, CT53518) is an orally active multitargeted tyrosine kinase inhibitor of FLT3 (IC50 = 0.22 μM), and it also inhibits c-Kit and PDGFR with IC50 values of 0.17 μM and 0.20 μM, respectively. Tandutinib has the ability to cross the blood-brain barrier. | ||
| M8506 | ML351 | Lipoxygenase |
| ML351 is a cell penetrant, selective and highly potent human lipoxygenase-12/15 (15-Lipoxygenase-1, 12/15-LOX) inhibitor that exhibits protective effects against oxidative glutamate toxicity in mouse neuronal HT22 cells. | ||
| M14901 | Tandutinib hydrochloride | FLT3 |
| MLN518 hydrochloride; CT53518 hydrochloride | ||
| Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. | ||
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