About 2 results found for searched term "ML167" (0.893 seconds)
Cat.No. | Name | Target |
---|---|---|
M2858 | ML167 | CDK |
CID 44968231 | ||
ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1-3 and Dyrk1A/1B. | ||
M10586 | JKE-1674 | Ferroptosis |
JKE1674 | ||
JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210. JKE-1674 reduces viability of LOX-IMVI cancer cells and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1. |
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