About 4 results found for searched term "ML 210" (0.131 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7650 | BML-210 | HDAC |
| BML-210 is a histone deacetylase inhibitor. | ||
| M8380 | ML 210 | Others |
| Ml-210 is a selective, covalent glutathione peroxidase 4 (GPX4) inhibitor with an EC50 of 30 nM. Ml-210 binds GPX4 selenocysteine residues. ML210 has anticancer activity and has shown cytotoxic effects on melanoma, lung adenocarcinoma, fibrosarcoma and pancreatic cancer cell lines. | ||
| M6979 | ML348 | Phospholipase |
| GNF-Pf-1127; ML-348 | ||
| ML348 is a selective and reversible lysophospholipase 1 (LYPLA1) inhibitor with an IC50 of 210 nM. | ||
| M10586 | JKE-1674 | Ferroptosis |
| JKE1674 | ||
| JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210. JKE-1674 reduces viability of LOX-IMVI cancer cells and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1. | ||
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