About 1 result found for searched term "MK-0731 " (0.162 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30678 | MK-0731 | Kinesin |
| MK-0731 is a selective, non-competitive and allosteric kinesin spindle protein (KSP) inhibitor with an IC50 of 2.2 nM and a pKa of 7.6. MK-0731 is >20,000 fold selectivity against other kinesins. MK-0731 induces mitotic arrest and induces apoptosis in tumors. MK-0731 provides significant antitumor efficacy. | ||
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