About 4 results found for searched term "ME-401" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11310 | Zandelisib | PI3K |
| ME-401; PWT-143 | ||
| Zandelisib (ME-401) is a PI3K inhibitor that selectively inhibits P110 δ with an IC50 value of 3.5 nM. Zandelisib has antitumor effects. | ||
| M20796 | ME-401 | PI3K |
| PWT-143, P110δ-IN-1 | ||
| ME-401 (PWT-143, P110δ-IN-1) is an oral, potent and selective inhibitor of Phosphatidylinositol 3-Kinase (PI3K) P110δ with IC50 of 0.6 nM in cellular assay. | ||
| M28443 | MM-401 | Histone Methyltransferase |
| MM-401 is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia. | ||
| M28444 | MM-401 TFA | Histone Methyltransferase |
| MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 µM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia. | ||
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