About 4 results found for searched term "MAP17" (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M50454 | MAP17 | Others |
| MAP17 (Cell-penetrating peptide MAP17) is a synthetic secondary amphipathic cell-penetrating peptides, with sequence of QLALQLALQALQAALQLA. | ||
| M54852 | MAP4K4-IN-3 | MAPKAPK2/MAP3K/MAP4K |
| MAP4K4-IN-3 (Compound 17) | ||
| MAP4K4-IN-3 is a potent and selective MAP4K4 inhibitor with an IC50 of 14.9 nM in kinase assay, and an IC50 of 470 nM in cell assay. | ||
| M7558 | SD-06 | p38 MAPK |
| SD-06 is a p38 MAP kinase inhibitor; inhibits p38α with an IC50 value of 170 nM and inhibits LPS-stimulated TNF-release in rats (83% inhibition at 1mg/kg, po). IC50 value: 170 nM Target: p38MAPK | ||
| M49369 | KP-14 | PROTAC |
| KP-14, a KRAS-PROTAC inhibitor with a similar structure to LC-2, inhibits the MAPK signaling pathway in NCI-H358 cells by binding to KRAS G12C via an acrylamide warhead and recruiting the E3 ligase CRBN, leading to rapid and sustained degradation of KRAS G12C. In addition, KP-14 exhibited potent antiproliferative activity against NCI-H358 cancer cells and was able to inhibit the formation of NCI-H358 tumor colonies, with an IC50 value of 17.41 μmol/L against the proliferation of NCI-H358 cells . | ||
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2024 AbMole BioScience. All Rights Reserved.
