About 1 result found for searched term "M8891 " (0.121 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M28501 | M8891 | Others |
| M8891 is an orally active, reversible and brain penetrant Methionine Aminopeptidase-2 (MetAP-2) inhibitor with an IC50 of 54 nM and a Ki of 4.33 nM. M8891 does not inhibit MetAP-1 (IC50>10 µM). M8891 inhibits growth of primary endothelial cells as well as tumor cells and demonstrates antiangiogenic and antitumoral activity. | ||
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