About 1 result found for searched term "Leriglitazone" (0.15 seconds)
Cat.No. | Name | Target |
---|---|---|
M21176 | Leriglitazone | PPAR |
Hydroxypioglitazone | ||
Leriglitazone (Hydroxypioglitazone), a metabolite of pioglitazone. Leriglitazone (Hydroxypioglitazone) is a PPARγ agonist that provides high transcriptional potency by stabilizing the PPARγ (AF-2) coactivator binding surface and enhancing coactivator binding capacity. Leriglitazone (Hydroxypioglitazone) binds to PPARγC (LBD) with a Ki value of 1.2 μM and induces PPARγ (LBD) transcriptional efficiency with an EC50 of 680 nM. |
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