About 2 results found for searched term "Leniolisib" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10186 | Leniolisib | PI3K |
| CDZ173 | ||
| Leniolisib (CDZ173) is a first-in-class (first-in-class), potent, selective PI3Kδ inhibitor with an IC50 value of 11 nM. Leniolisib has the potential for immunodeficiency disorders treatment. | ||
| M43397 | Leniolisib phosphate | PI3K |
| Leniolisib (CDZ173) phosphate is a first-in-class, potent and selective PI3Kδ inhibitor with an IC50 value of 11 nM.Leniolisib is more selective for PI3K-δ than PI3K-α (28-fold), PI3K-β (43-fold) and PI3K-γ (257-fold). -γ (257-fold). In a cellular assay, Leniolisib decreased pAKT pathway activity and inhibited the proliferation and activation of B and T cell subsets. | ||
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