About 6 results found for searched term "Lanosterol" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M17844 | Lanosterol | Metabolite/Endogenous Metabolite |
| Lanosterol is an intermediate of cholesterol synthesis and use of lanosterol induces ubiquitination and degradation of a rate-controlling enzyme of cholesterol synthesis, i.e., HMG CoA reductase. Lanosterol suppresses the aggregation and cytotoxicity of misfolded proteins linked with neurodegenerative diseases. | ||
| M30622 | Dihydrolanosterol | Cytochrome P450 (e.g. CYP17) |
| Dihydrolanosterol is a subtrate of CYP51 and a cholesterol biosynthesis inhibitor.. | ||
| M3953 | Voriconazole | Cytochrome P450 (e.g. CYP17) |
| UK-109496 | ||
| Voriconazole (UK-109496) is an inhibitor of 14α-lanosterol demethylase with IC50 value of 53 nM. Voriconazole (UK-109496) is also a second-generation, broad-spectrum triazole antifungal agent that inhibits fungal ergosterol biosynthesis. | ||
| M5581 | Diniconazole | Antibiotic |
| Rac-diniconazole | ||
| Diniconazole is a newly developed fungicide strongly inhibited lanosterol 14 alpha-demethylation catalyzed by a yeast cytochrome P-450. | ||
| M19437 | Uvariol | Others |
| Uvariol (21-Hydroxylanosterol) is a natural product that can be isolated from the roots of Piptostigma fugax. | ||
| M28201 | Quilseconazole | Antifungal |
| VT-1129 | ||
| Quilseconazole (VT-1129) is a potent, orally active fungal Cyp51 (lanosterol 14-α-demethylase) inhibitor, binds tightly to cryptococcal CYP51, but weakly inhibits humans CYP450 enzymes. | ||
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