About 4 results found for searched term "LW6" (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7896 | LWH-63 hydrochloride | Others |
| Non-peptide CRF1 corticotrophin-releasing factor antagonist. | ||
| M9279 | LW6 | HIF |
| HIF-1α inhibitor; CAY10585 | ||
| LW6 is a novel HIF-1alpha inhibitor, with an IC50 of 4.4 μM. LW6 decreases HIF-1α protein expression without affecting HIF-1β expression. | ||
| M45166 | LWY713 | PROTAC |
| LWY713 is a PROTAC molecule targeting FLT3 with acetyl group as linker, which can selectively induce FLT3 degradation in CRBN and proteasome-dependent manner, with a DC50 of 0.64 nM and a Dmax of 94.8%, and possesses antitumor activity. | ||
| M29819 | ZLWH-23 | AChR/AChE |
| ZLWH-23 is a selective AChE inhibitor (IC50=0.27 μM) with GSK-3β inhibitory property (IC50=6.78 μM). ZLWH-23 possesses selectivity for AChE over BChE (IC50=20.82 μM) and for GSK-3β over multi-kinases. ZLWH-23 has the potential for the research of Alzheimer's disease. | ||
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