About 2 results found for searched term "LP99 " (0.181 seconds)
Cat.No. | Name | Target |
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M28903 | (2S,3R)-LP99 | Epigenetic Reader Domain |
(2S,3R)-LP99 is a potent and selective BRD7 and BRD9 inhibitor with an KD of 99 nM for BRD9. (2S,3R)-LP99 inhibits the association of BRD7 and BRD9 to acetylated histones in vitro and in cells. (2S,3R)-LP99 demonstrates that BRD7/9 plays a role in regulating pro-inflammatory cytokine secretion. | ||
M28904 | LP99 | Epigenetic Reader Domain |
LP99, an epigenetic probe, is a potent and selective inhibitor of the BRD7 and BRD9 bromodomains with a Kd of 99 nM against BRD9. LP99 disrupts the binding of BRD7 and BRD9 to chromatin in cells. |
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