About 8 results found for searched term "LB-100" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M3013 | SKLB1002 | VEGFR/PDGFR |
| SKLB1002 is a potent and ATP-competitive VEGFR2 inhibitor with IC50 of 32 nM. | ||
| M8990 | LB-100 | PPAR |
| CAS# 1632032-53-1 | ||
| LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor, with IC50 of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. | ||
| M10433 | Bozitinib (PLB-1001) | c-Met |
| CBT-101; APL-101; CBI-3103; Vebreltinib | ||
| Bozitinib (PLB-1001; CBT-101) is a highly selective, blood-brain barrier permeable c-MET kinase inhibitor. | ||
| M8208 | 4-Phenylbutyryl hydroxamic acid | Others |
| 4-Phenylbutyryl hydroxamic acid is a cell permeable HDAC inhibitor which is about 100 times more potent than parent carboxylic acid among nine HDAC enzymes. | ||
| M20637 | SKLB-23bb | HDAC |
| SKLB-23bb is an orally bioavailable HDAC6-selective inhibitor with IC50 values under 100 nmol/L, against most of the cell lines checked. It also has microtubule-disrupting ability. | ||
| M21001 | Glycerol phenylbutyrate | Others |
| GT4P, HPN-100M, Ravicti | ||
| Glycerol phenylbutyrate (GT4P, HPN-100M, Ravicti) is a nitrogen-binding agent and acts as a sigma-2 (σ2) receptor ligand with a pKi of 8.02. Glycerol phenylbutyrate is a prodrug in which phenylbutyrate (PBA) is released from the glycerol backbone by lipases in the gastrointestinal tract. | ||
| M30695 | CMP8 | Estrogen Receptor |
| CMP8, a selective ligand for estrogen receptor, binds to the mutant estrogen receptor ligand binding domain (ERLBD). CMP8 exhibits IC50 values of 29 nM , 41 nM, 1100 nM and 2200 nM for MGERα, MGRERα, hERα and hERβ, respectively. | ||
| M38634 | 10-Isobutyryloxy-8,9-epoxythymol isobutyrate | Antibiotic |
| 10-Isobutyryloxy-8,9-epoxythymol isobutyrate shows moderate antimicrobial activity against Staphylococcus aureus FDA 209 P, Staphylococcus aureus, Enterococcus faecalis, Candida albicans and Pseudomonas aeruginosa with MICs of 50, 250, 250, 250, and 1000 μg/mL, respectively. | ||
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