About 5 results found for searched term "Ketohexokinase" (0.123 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M21287 | PF-06835919 | Ketohexokinase |
| Ketohexokinase inhibitor 1 | ||
| PF-06835919 is an oral Class I clinical candidate for NAFLD/NASH, targeting ketohexokinase (KHK), an enzyme that initiates fructose metabolism. | ||
| M28138 | KHK-IN-1 | Ketohexokinase |
| KHK-IN-1 (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 has potential for the study of diabetes and obesity. | ||
| M28139 | KHK-IN-1 hydrochloride | Ketohexokinase |
| KHK-IN-1 hydrochloride (compound 8) is a selective and cell membrane permeable ketohexokinase (KHK) inhibitor (IC50=12 nM; F=34%). KHK-IN-1 hydrochloride inhibits the production of F1P in HepG2 cell lysates (IC>sub>50=400 nM). KHK-IN-1 hydrochloride has potential for the study of diabetes and obesity. | ||
| M29288 | KHK-IN-2 | Ketohexokinase |
| KHK-IN-2 is a potent and selective ketohexokinase (KHK) inhibitor with an IC50 of 0.45 μM. | ||
| M43110 | KHK-IN-3 | Ketohexokinase |
| LY3522348 | ||
| KHK-IN-3 is a ketohexokinase (KHK) inhibitor. | ||
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