About 1 result found for searched term "KY02111" (0.154 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2800 | KY02111 | Others |
| KY02111 is a widely used small molecule that boosts cardiomyogenesis. Chemical genetics of KY02111 identified squalene synthase (SQS) as a molecular target of KY02111. By disrupting the interaction of SQS with cardiac ER-membrane protein TMEM43, KY02111 impairs TGFβ/SMAD signaling and recapitulates the clinical mutation of TMEM43 that causes an inherited heart disease. | ||
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