JNK2-IN-1 - Search Results | AbMole BioScience

About 5 results found for searched term "JNK2-IN-1" (0.115 seconds)

Cat.No.	Name	Target
M42127	JNK2-IN-1	JNK
	JNK2-IN-1 is a JNK2 inhibitor (Kds: 79.2 μM).
M9388	Tanzisertib	JNK
	CC-930
	Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
M10633	AS601245	JNK
	AS-601245
	AS601245 is an orally active, selective, ATP competitive JNK (c-Jun NH2-terminal protein kinase) inhibitor with IC50 values of 150, 220, and 70 nM for JNK human isoforms (hJNK1, hJNK2, and hJNK3), respectively.
M42123	JNK-IN-12	JNK
	JNK-IN-12 is a mitochondrial-targeted JNK inhibitor (IC50=66.3 nM), consisting of a mitochondrial-specific cell-penetrating peptide and a specific inhibitor of JNK, SP600125.
M55643	SKLB-163	Apoptosis
	SKLB163
	SKLB-163 is an orally active inhibitor for Rho GDP-dissociation (RhoGDI). SKLB-163 acts by downregulating RhoGDI, activating JNK-1 signaling pathway and caspase-3, and reducing phosphorylated Akt and p44/42 MAPK. SKLB-163 inhibits highly expressed RhoGDI tumor cell proliferation and migration, and increases radiosensitivity of tumor cells. SKLB-163 induces cancer cell Apoptosis.