About 1 result found for searched term "JNJ-39758979" (0.06 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M11287 | JNJ-39758979 | Histamine Receptor |
| Jnj-39758979 is a selective, orally active, high-affinity histamine H4 receptor antagonist with Ki values of 12.5, 5.3 and 25 nM for human, mouse and monkey histamine H4 receptor, respectively. Jnj-39758979 antagonized histamine-induced cAMP inhibition with a pA2 of 7.9. Jnj-39758979 has good anti-inflammatory and antipruritic effects. | ||
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