About 1 result found for searched term "JNJ-26489112 " (0.12 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M30775 | JNJ-26489112 | Calcium Channel |
| JNJ-26489112, a CNS-active agent, exhibits broad-spectrum anticonvulsant activity in rodents against audiogenic, electrically-induced, and chemically-induced seizures. JNJ-26489112 inhibits voltage-gated Na+ channels and N-type Ca2+ channels, and is effective as a K+ channel opener. JNJ-26489112 has very weak inhibition of CA-II (IC50=35 μM) and CA-I (18 μM). | ||
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