About 1 result found for searched term "JKE-1674" (0.232 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10586 | JKE-1674 | Ferroptosis |
| JKE1674 | ||
| JKE-1674 is an inhibitor of glutathione peroxidase 4 (GPX4) and an active metabolite of the GPX4 inhibitor ML-210. JKE-1674 reduces viability of LOX-IMVI cancer cells and in a panel of additional cancer cell lines, an effect that can be blocked by the ferroptosis inhibitor ferrostatin-1. | ||
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