About 2 results found for searched term "JBSNF-000088 (6-Methoxynicotinamide)" (0.122 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M9681 | JBSNF-000088 (6-Methoxynicotinamide) | Others |
| 6-Methoxynicotinamide | ||
| Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide (NA) analogue, which is a potent NNMT inhibitor. Jbsnf-000088 (6-methoxynicotinamide) is a niacinamide n-methyl transferase (NNMT) inhibitor. The IC50 of monkey NNMT and mouse NNMT were 1.8 µM, 2.8 µM and 5.0 µM, respectively. In animal models of metabolic diseases, JBSNF-000088 inhibits NNMT activity, reduces MNA levels and drives insulin sensitization and regulates glucose. | ||
| M11322 | JBSNF-000088 | Others |
| 6-Methoxynicotinamide | ||
| Jbsnf-000088 (6-methoxynicotinamide) is an analogue of Nicotinamide (NA), and is an effective inhibitor of Nicotinamide n-methyltransferase (NNMT). The IC50 values for human NNMT(hNNMT), Monkey NNMT(mkNNMT) and mouse NNMT(mNNMT) were 1.8 µM, 2.8 µM and 5.0 µM. | ||
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