About 2 results found for searched term "JAK3 covalent inhibitor-1" (0.118 seconds)
Cat.No. | Name | Target |
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M49586 | JAK3 covalent inhibitor-1 | JAK |
JAK3 covalent inhibitor-1 is a potent and selective janus kinase 3 (JAK3) covalent inhibitor with an IC50 of 11 nM and shows 246-fold selectivity vs other JAKs. | ||
M11227 | FM-479 | JAK |
Fm-479 was a negative control of FM-381 and showed no activity against JAK3 or other kinases. Fm-381 is a potent covalent reversible inhibitor of JAK3 targeting unique Cys909. For JAK3, FM-381 was 410, 2700 and 3600 times more selective than JAK1, JAK2 and TYK2 with IC50 of 127 pM. |
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