About 1 result found for searched term "Iberdomide" (0.152 seconds)
Cat.No. | Name | Target |
---|---|---|
M6072 | Iberdomide | E1/E2/E3 Enzyme |
CC220; CC 220; CC-220 | ||
Iberdomide (CC-220) is an orally effective cereblon (CRBN) E3 ligase modulator (CELMoD) with an IC50 for cereblon binding affinity of approximately 150 nM. Iberdomide (CC-220) binds CRBN with higher affinity than lenalidomide and pomalidomide and has enhanced degradation of IKZF1 and IKZF3 with enhanced degradation. |
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