About 3 results found for searched term "IWP-2" (0.13 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2237 | IWP-2 | Wnt/beta-catenin |
| Inhibitor of Wnt Production-2 | ||
| IWP-2 is an inhibitor of Wnt production that impairs Wnt pathway activity in vitro with an IC50 value of 27 nM. | ||
| M30489 | IWP-12 | Transferase |
| IWP-12 is a potent inhibitor of porcupine (PORCN) and inhibits cell-autonomous Wnt signaling with an IC50 of 15 nM. | ||
| M20629 | IWP-O1 | Wnt/beta-catenin |
| IWP-O1 is a porcn inhibitor with an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling and effectively suppresses the phosphorylation of Dvl2/3 in HeLa cells. | ||
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