IV-275 - Search Results | AbMole BioScience

About 5 results found for searched term "IV-275" (0.132 seconds)

Cat.No.	Name	Target
M41662	IV-275	Epigenetic Reader Domain
	IV-275 is an inhibitor of both BRG1 and BRM bromodomains.
M1942	Alectinib	ALK
	CH5424802; AF802
	Alectinib (CH5424802) is a highly selective, orally active and potent ALK inhibitor with IC50 of 1.9 nM. Alectinib (CH5424802) also inhibits ALK F1174L and ALK R1275Q with IC50s of 1 nM and 3.5 nM, respectively. Alectinib demonstrates effective central nervous system (CNS) penetration.
M50214	AC 187 TFA	Amyloid
	AC 187 TFA is a potent, orally active and neuroprotective amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM. AC 187 TFA is more selective for amylin receptors than calcitonin and CGRP receptors.
M53274	AC 187	Others
	AC 187 is a potent and orally active amylin receptor antagonist with an IC50 of 0.48 nM and a Ki of 0.275 nM.
M55627	RO-275	HCN Channel
	RO-275 is a potent, selective and orally active HCN1 inhibitor with IC50 values of 0.046, 14.3, 4.6, 13.9 µM for HCN1, HCN2, HCN3, HCN4, respectively. The selective HCN1 inhibitor RO-275 improved performance in a translationally relevant touchscreen task of WM (TUNL) in rats.