About 28 results found for searched term "IOX2" (0.057 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M2573 | IOX2 | HIF |
| IOX2 is a potent inhibitor of HIF-1α prolyl hydroxylase-2 (PHD2) with IC50 of 21 nM, >100-fold selectivity over JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH. | ||
| M13340 | Uric acid | Animal Modeling |
| 2,6,8-Trioxypurine；2,6,8-Trihydroxypurine | ||
| Uric acid is a scavenger of oxygen radical, a very important antioxidant and a product of the metabolic decomposition of purine nucleotides. Helps maintain stable blood pressure and fights oxidative stress. Uric acid removes reactive oxygen species (ROS) such as singlet oxygen and peroxynitrite and inhibits lipid peroxidation. It can be used to induce animal models of uric acid nephropathy. | ||
| M16895 | 2,3-Di(3',4'-methylenedioxybenzyl) -2-buten-4-olide | Lignans |
| 2,3-Di(3',4'-methylenedioxybenzyl) -2-buten-4-olide | ||
| M16993 | 2-(2,2-Dimethyl-1,3-dioxolan -4-yl)propane-1,2-diol | Others |
| 2-(2,2-Dimethyl-1,3-dioxolan -4-yl)propane-1,2-diol | ||
| M16994 | 1,6-Dioxaspiro[4.5]decan-2-methanol | Others |
| 1,6-Dioxaspiro[4.5]decan-2-methanol | ||
| M17940 | (3β,7β,12β,20Z )-3,7,12-trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid | Others |
| （3β,7β,12β,20Z ）- 3,7,12- trihydroxy-11,15,23-trioxo-lanost-8,20-dien-26-oic acid | ||
| M17946 | Lanosta-8,20 (22)-dien-26-oic acid, 15-hydroxy-3,11,23-trioxo-, (15α,20Z)- | Others |
| Lanosta-8,20（22）-dien-26-oic acid, 15-hydroxy-3,11,23-trioxo-, （15α,20Z）- | ||
| M28559 | (R)-FL118 | Others |
| 10,11-(Methylenedioxy)-20(R)-camptothecin | ||
| (R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118. (R)-FL118 shows anticancer activity. | ||
| M43876 | 1,1-Dimethylethyl 6-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-2(1H)-isoquinolinecarboxylate | Ligand for E3 Ligase |
| 1,1-Dimethylethyl 6-(2,6-dioxo-3-piperidinyl)-3,4-dihydro-2(1H)-isoquinolinecarboxylate | ||
| M30730 | 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol | Apoptosis |
| 9,11-Dehydroergosterol peroxide; 9(11)-DHEP | ||
| 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol (9,11-Dehydroergosterol peroxide), an important steroid from medicinal mushroom, exerts antitumor activity in several tumor types. 5,8-Epidioxyergosta-6,9(11),22-trien-3-ol inhibits HT29 cell growth by inducing CDKN1A expression, thus causing cell cycle arrest and apoptosis. | ||
| M38771 | 1,4-Epidioxybisabola-2,10-dien-9-one | Anti-infection |
| 1,4-Epidioxybisabola-2,10-dien-9-one is a 1,4-epidioxy-bisabola-2,12-diene derivate, which can be isolated from Curcuma longa L. 1,4-Epidioxybisabola-2,10-dien-9-one exhibits antiviral activity against influenza virus A/PR/8/34 (H1N1) in the MDCK cell line with an IC50 of 16.79 ± 4.03 μg/mL. | ||
| M40879 | [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid | ADC Linker |
| Fmoc-8-amino-3,6-dioxaoctanoic acid; Fmoc-NH-PEG2-CH2COOH | ||
| [2-[2-(Fmoc-amino)ethoxy]ethoxy]acetic acid is a PEG-based degradable ADC linker and PROTAC linker that can be used in the synthesis of antibody active molecule couplers (ADCs) and PROTACs. | ||
| M43850 | 2-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-2-azaspiro[3.3]heptane-6-acetic acid | Ligand for E3 Ligase |
| 2-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-2-azaspiro[3.3]heptane-6-acetic acid | ||
| M43851 | 1-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-4-piperidineacetic acid | Ligand for E3 Ligase |
| 1-[5-(2,6-Dioxo-3-piperidinyl)-2-pyridinyl]-4-piperidineacetic acid | ||
| M43860 | 1-[5-(2,6-Dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]-4-piperidineacetic acid | Ligand for E3 Ligase |
| 1-[5-(2,6-Dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]-4-piperidineacetic acid | ||
| M43861 | 4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]-, 1,1-dimethylethyl ester | Ligand for E3 Ligase |
| 4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]-, 1,1-dimethylethyl ester | ||
| M43862 | 4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- | Ligand for E3 Ligase |
| 4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- | ||
| M43864 | 4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- | Ligand for E3 Ligase |
| 4-Piperidinecarboxylic acid, 1-[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]- | ||
| M43865 | Cyclohexanecarboxaldehyde, 4-[[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]oxy]-, trans- | Ligand for E3 Ligase |
| Cyclohexanecarboxaldehyde, 4-[[5-(2,6-dioxo-3-piperidinyl)-2-pyridinyl]oxy]-, trans- | ||
| M43872 | 4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]- | Ligand for E3 Ligase |
| 4-Piperidinecarboxaldehyde, 1-[5-(2,6-dioxo-3-piperidinyl)-3-fluoro-2-pyridinyl]- | ||
| M43881 | 1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-3-pyrrolidinecarboxaldehyde | Ligand for E3 Ligase |
| 1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-3-pyrrolidinecarboxaldehyde | ||
| M43882 | 1-(4-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)phenyl)piperidine-4-carbaldehyde | Ligand for E3 Ligase |
| 4-Piperidinecarboxaldehyde, 1-[4-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]- | ||
| 1-(4-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)phenyl)piperidine-4-carbaldehyde | ||
| M43884 | 1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-4-piperidinecarboxylic acid | Ligand for E3 Ligase |
| 1-[4-(Tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)phenyl]-4-piperidinecarboxylic acid | ||
| M43887 | 1-(5-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)pyridin-2-yl)piperidine-4-carbaldehyde | Ligand for E3 Ligase |
| 4-Piperidinecarboxaldehyde, 1-[5-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)-2-pyridinyl]- | ||
| 1-(5-(2,4-Dioxotetrahydropyrimidin-1(2H)-yl)pyridin-2-yl)piperidine-4-carbaldehyde | ||
| M43892 | 3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-fluorobenzoic acid | Ligand for E3 Ligase |
| Benzoic acid, 4-fluoro-3-(tetrahydro-2,4-dioxo-1(2H)-pyrimidinyl)- | ||
| 3-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-4-fluorobenzoic acid | ||
| M43915 | 2,6-bis(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | Ligand for E3 Ligase |
| 2,6-Bis(benzyloxy)pyridine-3-boronic Acid Pinacol Ester | ||
| 2,6-bis(benzyloxy)-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine | ||
| M44596 | 11alpha-hydroxy-3,7-dioxo-5alpha-lanosta-8,24(E)-dien-26-oic acid | Others |
| 11alpha-hydroxy-3,7-dioxo-5alpha-lanosta-8,24(E)-dien-26-oic acid | ||
| M52214 | 2-(1, 3-Dioxoisoindolin-2-yl)pentanedioic acid | Amino Acid Derivatives |
| 2-(1,3-Dioxoisoindolin-2-yl)pentanedioic acid is a glutamic acid derivative. | ||
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