About 2 results found for searched term "IDO1-IN-22" (0.137 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M42449 | IDO1-IN-22 | IDO |
| IDO1-IN-22 is a IDO1 inhibitor (biochemical hIDO1 IC50: 67.4 nM, HeLa hIDO1 IC50: 17.6 nM). | ||
| M29809 | NU223612 | PROTAC |
| NU223612 is a potent PROTAC (PROTACs) that degrades indoleamine 2,3-dioxygenase 1 (IDO1) (Indoleamine 2,3-Dioxygenase (IDO)) with a Kd of 640 nM. NU223612 potently degrades the IDO1 protein through CRBN-mediated proteasomal degradation. NU223612 is bound to CRBN with an affinity of 290 nM. NU223612 can cross the blood-brain barrier (BBB). | ||
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