IA9 TFA - Search Results | AbMole BioScience

About 4 results found for searched term "IA9 TFA" (0.382 seconds)

Cat.No.	Name	Target
M55317	IA9 TFA	Immunology/Inflammation
	human TREM-2 182-190 TFA
	IA9 TFA is a TREM-2 inhibitor. IA9 TFA and can diminish release of proinflammatory cytokines and dramatically suppressed joint inflammation and damage in collagen-Induced Arthritis (CIA) mice model.
M11321	Angiopeptin TFA	Somatostatin Receptor
	Angiopeptin TFA, a cyclic octapeptide analog of somatostatin, is an SST2 / SST5 receptor partial agonist with IC50 values of 0.26 nM and 6.92 nM, respectively. Angiopeptin TFA inhibits growth hormone release and insulin-like growth factor-1 (IGF-1) production. Angiopeptin TFA inhibits adenylate cyclase or stimulates extracellular acidification. Angiopeptin TFA has the potential to be used in the study of coronary atherosclerosis.
M21507	AS-99 TFA	Histone Methyltransferase
	AS-99 TFA is the first-in-class, effective and selective ASH1L histone methyltransferase inhibitor (IC50= 0.79 µM, Kd= 0.89 µM) with anti-leukemia activity. In vivo, AS-99 TFA blocked cell proliferation, induced apoptosis and apoptosis, down-regulated MLL fusion target genes, and alleviated leukaemia.
M49451	MSG606 TFA	Melanocortin Receptor
	MSG606 TFA is a potent human MC1 receptor antagonist (IC50=17 nM) and a partial agonist at human MC3 and MC5 receptors (EC50 values of 59 and 1300 nM, respectively). In addition, MSG606 TFA reversed the hyperalgesia induced in female mice but had no effect in male mice.