About 18 results found for searched term "Hyp9" (0.125 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M7844 | Hyp9 | Others |
| Hyperforin is the active ingredient in St. | ||
| M52942 | Hypocretin (70-98), human | OX Receptor |
| Hypocretin (70-98), human is a polypeptide that is capable of binding to an orexin receptor OX1R and promotes apoptosis. | ||
| M58517 | 2'-Deoxyinosine | Metabolite/Endogenous Metabolite |
| 2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability. | ||
| M2206 | TH-302 (Evofosfamide) | Others |
| Evofosfamide | ||
| TH-302 is a highly potent and selective hypoxia-activated procompound targeting hypoxic regions of solid tumors with IC50 of 19 nM. | ||
| M4027 | Hypaconine | Others |
| Hypaconine is a C19-diterpenoid alkaloid isolated from aconitum, and shows strong cardiac activity. | ||
| M6401 | Acifran | Others |
| Acifran is a hypolipidemic agent; agonist for the GPR109A (HM74A) and GPR109B receptors. | ||
| M7828 | Hypothemycin | Others |
| Hypothemycin, one of the highly oxygenated analogues in the group of 14-membered resorcylic acid lactones (RAL), has minor antifungal and cytotoxic activity and exhibits an in vitro anti-malarial activity with an IC50 of 2. | ||
| M8424 | KC7F2 | HIF |
| KC7F2 is a cell permeable potent hypoxia inducible factor-1 (HIF-1) pathway inhibitor, with IC50 of 20 μM in LN229-HRE-AP cells, and with potential as a cancer therapy agent. | ||
| M9033 | VH-298 | Ligand for E3 Ligase |
| VH298 | ||
| VH-298 is a potent VHL inhibitor that stabilizes HIF-α and elicits a hypoxic response via a different mechanism, with a Kd value of 80 to 90 nM. | ||
| M11488 | Recombinant Human PDGF-BB (E. coli) | Cytokines and Growth Factors |
| PDGFBB; PDGF-BB | ||
| PDGF has three subforms: PDGF-AA, PDGF-BB, PDGF-AB. It is involved in a number of biological processes, including hyperplasia, embryonic neuron development, chemotaxis, and respiratory tubule epithelial cell development. Protein structure: PDGF-BB (Ser82-Thr190) | ||
| M14448 | Echinomycin | HIF |
| Quinomycin A; NSC-13502 | ||
| Echinomycin (Quinomycin A) is potent small-molecule and cell-permeable inhibitor of hypoxia-inducible factor-1 (HIF-1) DNA-binding activity. Echinomycin selectively inhibits the cancer stem cells (CSCs) with an IC50 of 29.4 pM. | ||
| M25441 | Recombinant Human Endothelin B Receptor Protein (HEK293, His Tag) | Cytokines and Growth Factors |
| human EDNRB | ||
| EDNRB is a new candidate tumor suppressor gene which is often down-regulated or even silenced by promoter hypermethylation in various human cancers. The recombinant human EDNRB consists 86 amino acids and predicts a molecular mass of 9.5 kDa. A DNA sequence encoding the human EDNRB (NP_000106.1) (Met1-Lys101) was expressed with a polyhistidine tag at the C-terminus. | ||
| M28340 | Chetomin | HSP |
| Chetomin, an active component of Chaetomium globosum, is a heat shock protein 90/hypoxia-inducible factor 1 alpha (Hsp90/HIF1α) pathway inhibitor. Chetomin is a potent, nontoxic non-small cell lung cancer cancer stem cells (NSCLC CSC)-targeting molecule. | ||
| M30431 | RGW-611 | Others |
| RGW 611 is a morpholine derivative that enhances radiation-induced cell death of hypoxic V79-379A cells. | ||
| M31361 | Recombinant Human MRAP Protein (HEK293, hFc Tag) | Cytokines and Growth Factors |
| Melanocortin 2 Receptor Accessory Protein; FALP; B27 | ||
| MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. A DNA sequence encoding the human MRAP (Tyr59-Ser172) was expressed with the Fc region of human IgG1 at the N-terminus. | ||
| M40970 | Hydroethidine | Fluorescent Dye |
| Hydroethidine is a peroxide indicator that freely enters cells and dehydrogenates into ethidium bromide and distinguishes between superoxide and H2O2, and can be used to identify proliferating and hypoxic cells in tumors (λex=520 nm, λem=600 nm). This product has been merged into M9696 | ||
| M50898 | H-Gly-Pro-Hyp-OH | Others |
| HGly-Pro-Hyp-OH (Tripeptide 29) is an orally active bioactive peptide against UVB-induced skin aging and has been reported used as a cosmetic ingredient. | ||
| M54130 | HIF-1 alpha (556-574) | Others |
| HIF-1 alpha (556-574) is a short hypoxia-inducible factor-1 (HIF-1) 19 residues fragment. | ||
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