About 3 results found for searched term "Huwentoxin-IV" (0.103 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M10458 | Huwentoxin IV TFA | Sodium Channel |
| Huwentoxin-IV | ||
| Huwentoxin IV TFA is a selective NaV1.7 channel blocker, which preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM). | ||
| M52722 | Huwentoxin-IV | Sodium Channel |
| Huwentoxin-IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively. | ||
| M58140 | HwTx-IV | Sodium Channel |
| Huwentoxin-IV | ||
| Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. Huwentoxin-IV, a component of tarantula venom, potently blocks sodium channels and is an attractive scaffold for engineering a Nav1.7-selective molecule. | ||
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