Huwentoxin I - Search Results | AbMole BioScience

About 5 results found for searched term "Huwentoxin I" (0.056 seconds)

Cat.No.	Name	Target
M10458	Huwentoxin IV TFA	Sodium Channel
	Huwentoxin-IV
	Huwentoxin IV TFA is a selective NaV1.7 channel blocker, which preferentially inhibits neuronal NaV1.7, 1.2 and 1.3 (IC50 values are 26, 150 and 338 nM respectively), compared to muscle subtypes NaV1.4 and 1.5 (IC50 = >10 μM).
M52722	Huwentoxin-IV	Sodium Channel
	Huwentoxin-IV is a potent and selective sodium channel blocker, inhibits neuronal Nav1.7, Nav1.2, Nav1.3 and Nav1.4 with IC50s of 26, 150, 338 and 400 nM, respectively.
M52799	Huwentoxin I	Calcium Channel
	Huwentoxin I (HWTX-I) is a peptide toxin that inhibits voltage-gated sodium channels and N-type calcium channels.
M52802	Huwentoxin XVI	Calcium Channel
	Huwentoxin XVI, an analgesic, is a highly reversible and selective mammalian N-type calcium channel (IC50 of ~60 nM) antagonist from Chinese tarantula Ornithoctonus huwena.
M58140	HwTx-IV	Sodium Channel
	Huwentoxin-IV
	Huwentoxin-IV (HwTx-IV) is a 35-residue neurotoxin peptide with potential application as a novel analgesic. Huwentoxin-IV, a component of tarantula venom, potently blocks sodium channels and is an attractive scaffold for engineering a Nav1.7-selective molecule.